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Steven Jay

Associate Professor
Fischell Department of Bioengineering
3116 A. James Clark Hall
smjay@umd.edu
301-405-2829
Jay Research Group

EDUCATION

  • 2009 - 2013    Postdoctoral Fellow, Brigham and Women's Hospital/Harvard Medical School (PI: Richard T. Lee)
  • 2009 - 2013    Visiting Scientist, MIT (PI: Linda Griffith)
  • 2004 - 2009    PhD, Yale University (PI: W. Mark Saltzman)
  • 2000 - 2004    BSBE, University of Georgia

HONORS AND AWARDS

  • 2018     Graduate Faculty Mentor of the Year – University of Maryland
  • 2018     CAREER Award – National Science Foundation
  • 2018     Associate Scientific Advisory Board Member – Science Translational Medicine
  • 2016     Faculty Teaching Award – Fischell Department of Bioengineering, U. of Maryland
  • 2016     Young Innovator in Cellular and Molecular Bioengineering – Biomedical Engineering Society
  • 2015     Ralph E. Powe Junior Faculty Award – Oak Ridge Associated Universities
  • 2013     Innovation and Career Development Award – Biomedical Engineering Society (BMES)
  • 2012     Innovative Technology in Cardiovascular Sciences Award – Brigham and Women’s Hospital
  • 2012     Innovation in Biotechnology Award – American Association of Pharmaceutical Scientists
  • 2012     K99/R00 Pathway to Independence Award – National Institutes of Health
  • 2011     Breast Cancer Postdoctoral Fellowship – U.S. Department of Defense
  • 2010     F32 NRSA Postdoctoral Fellowship – National Institutes of Health (declined)
  • 2009     Henry Prentiss Becton Prize (Outstanding Ph.D. Thesis in Engineering) – Yale University

PROFESSIONAL MEMBERSHIPS

  • Biomedical Engineering Society (BMES)
  • International Society for Extracellular Vesicles (ISEV)
  • American Society of Gene & Cell Therapy (ASGCT)
  • Society for Biological Engineering (SBE)
  • American Association of Pharmaceutical Scientists (AAPS)

 

RESEARCH AREAS

Extracellular vesicles, cell therapy, protein therapeutics, drug delivery, biomanufacturing

LAB OVERVIEW

Our research aims to uncover new biological insights towards the design and development of novel biotherapeutics (aka biopharmaceuticals), including proteins, extracellular vesicles (exosomes) and others. We also strive to develop new approaches to drug delivery and biomanufacturing using fundamental tools from both engineering and biology. Employing techniques in molecular biology, protein design and engineering, biomaterials and nanotechnology, we are primarily interested in developing new biotechnologies to address clinical needs in wound repair, cardiovascular disease, cancer, brain and spinal cord injuries, neurological diseases, osteoarthritis, and sepsis, among others. Overarching goals of the lab include developing therapeutics towards clinical translation and endowing trainees with the skills and knowledge necessary to become leaders in the biotechnology and pharmaceutical industries.

PUBLICATIONS

Google Scholar Profile

  • BIOE340 - Modeling Physiological Systems 
  • BIOE389C - Bioengineering Design Competitions 
  • BIOE462 - Therapeutic Development and Delivery 
  • BIOE612 - Physiological Evaluation of Bioengineering Designs 

BIOE Students Earn Top Honors for Health Innovation at 2025 Capstone Expo
BIOE and BCE students showcased innovative health tech solutions at the 2025 Capstone Design Expo.

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